Drug News (Medindia)

New Drug Combination for High-Risk Neuroblastoma

Researchers create novel combination as potential therapy for high-risk neuroblastoma. This combination is made of epigenetic inhibitors and B-cell lymphoma 2 (BCL-2) inhibitors. BCL-2 inhibitors are already approved by the U.S. Food and Drug Administration.

Online Scoring System to Help Choose Therapies for Chronic Hepatitis C

BIDMC researchers develop decision-making tool to benefit patients with Chronic Hepatitis C (HCV). The online scoring system, called the BE3A score, assesses five baseline factors - body mass index, encephalopathy, ascites and serum levels of alanine aminotransferase and albumin.

Diagnosis of Liver Diseases in Teenagers Made Easy

New ultrasound technology called Time-Harmonic Elastography (THE) can diagnose liver diseases in teenagers based on its ability to measure elasticity in tissues. This measure is noninvasive compared to the current methods such as liver biopsy.

Here's How Zika Virus Works in Humans and Animals

Princeton scientists uncover a factor important for ZIKA Virus host species restriction in a study of humans and animals. The study identified one of the mechanisms by which ZIKA virus (ZIKV) circumvents immune control to replicate in human cells.

Method to Improve Birthweight of IVF Babies Identified

A method to improve the birth-weight of babies born through in vitro fertilization (IVF) has been identified. Children derived from fresh embryo transfer have smaller birth weight and children derived from frozen embryo transfer have higher birth weight in average.

Preserving a Young Cancer Patient's Fertility With Cell Culture System

New method to preserve boy cancer patient's fertility has been developed at American Associates, Ben-Gurion University of The Negev. This study may open the way for new therapeutic strategies for fertility preservation of prepubertal cancer patient boys (PCPBs).

What Happens to the Brain When We Touch Cold Objects?

Neuroscientists map brain's response to cold touch and find that the posterior insula is specialized for somatosensory information encoding temperature, pain, and gentle touch. The team finds that the insula can be activated with inhaled menthol to see the same reaction.

DNA Synthesis Made Faster and Cheaper

A key enzyme in DNA synthesis has been found by scientists, which plays a unique and different role to speed up the process.

Connections in the Brain Linked to Rheumatoid Arthritis Inflammation

How the brain plays a role in rheumatoid arthritis inflammation - a pattern of connections spanning 49 regions associated with peripheral inflammation has been identified by recent research. These regions play a critical role in rheumatoid arthritis.

Risky Opioid Prescriptions May Up Mortality Risk

Risky opioid prescriptions may increase mortality risk. As the number of risky opioid prescriptions increases, the chance of dying and their odds of death also goes higher.

Daily Fasting May Improve Weight Loss

Daily fasting based on time-restricted eating, the 16:8 diet named for its 16 hours of fasting and its 8 hours of feasting may reduce weight loss and lower blood pressure.